Research shows that ketamine can significantly reduce depressive symptoms by promoting neuroplasticity, allowing the brain to form new, healthier neural pathways. This helps interrupt rigid, negative thought patterns that often drive long-term depression and emotional distress.
Many patients report noticeable improvements in mood, motivation, and outlook on life within hours or days of treatment, which is rarely seen with traditional antidepressants. In clinical settings, ketamine has also demonstrated a strong ability to reduce suicidal ideation, making it a potentially life-saving option for individuals in acute distress.
Ketamine therapy is most commonly recommended for individuals who have not responded to standard approaches, such as antidepressant medications or talk therapy. Candidates typically include those who have not experienced relief from two or more antidepressants, struggled with side effects, or continue to experience persistent symptoms despite care.
When delivered in a structured, medically supervised environment and paired with psychotherapy, ketamine therapy can lead to meaningful, sustained improvements in mental health and overall quality of life.
Unlike traditional antidepressants that primarily target serotonin, ketamine works on the brain’s glutamate system, a key pathway involved in mood regulation, learning, and neuroplasticity. By blocking NMDA receptors and increasing glutamate activity, ketamine stimulates the release of brain-derived neurotrophic factor (BDNF), which helps strengthen and rebuild neural connections that are often impaired in depression.
One of ketamine’s most notable benefits is its rapid onset of action. Many patients experience symptom relief within hours or days rather than weeks, making it especially valuable for individuals with treatment-resistant depression or acute suicidal thoughts. This fast-acting effect can create a critical window of stability and hope while longer-term therapies take effect.
In addition to improving mood, ketamine has been shown to reduce suicidal ideation, increase emotional flexibility, and interrupt negative thought patterns. When combined with psychotherapy and ongoing mental health support, ketamine therapy can help patients gain new perspectives, process emotional distress, and sustain meaningful improvements in their overall well-being.
At Harper Clinic Utah, your care team works closely with you to monitor progress, adjust treatment as needed, and support long-term healing and recovery.
Before your session, you complete a comprehensive medical and mental health evaluation to determine if ketamine therapy is appropriate for you. This includes a review of your psychiatric history, current medications, physical health, and treatment goals.
During your session, you will be placed in a comfortable, calm setting designed to promote relaxation. As the ketamine takes effect, you may experience changes in perception, heightened introspection, or a sense of emotional release.
These effects are temporary and closely monitored throughout the session. You are encouraged to rest, listen to music, or relax during the experience. Sessions typically last 60 to 90 minutes, depending on the method and individual response.
You may bring a support person with you to sit in the room. Our nurse will be there to help guide the session in a positive manner, using native american medicines such as Sage, Palo Santo, Behr Root, etc. They also get a guided journal with prompted questions to reflect before and after the appointment to help set intentions and bring notes back to their therapist.
We accept most major insurance providers. Contact our treatment coordination team today to verify your benefits or discuss flexible payment options.
Ketamine is delivered in a controlled, medically supervised environment. During sessions, patients are closely monitored for safety and comfort, ensuring a safe and comfortable treatment process. Our protocols are designed to maximize benefits while minimizing risks, making ketamine therapy a safe option.
Our experienced clinical team understands the complexity of treatment-resistant depression, anxiety, and mood disorders and tailors ketamine protocols to each patient’s unique history, symptoms, and goals. By using evidence-based dosing, careful monitoring, and ongoing assessment, we prioritize safety, personalization, and long-term outcomes.
Ketamine therapy integrates well with other advanced treatments at Harper Clinic, such as , trauma-processing therapies, and holistic wellness practices, including massage and yoga. This approach helps patients deepen their healing and maintain longer-term symptom relief. Patients are required to meet with a therapist within 24 to 48 hours of ketamine treatment, either through Harper Clinic or another provider.
We accept most major insurance plans, and many cover ketamine therapy, particularly for treatment-resistant depression.
Ketamine treatment costs in Utah vary by clinic and how the treatment is delivered. Insurance may cover or typically at least partially reimburse for Major Depressive Disorder.
Our cash pay price with no insurance starts at $300 per appointment. Financing with Care Credit is available.
Common side effects include mild dissociation, dizziness, nausea, increased blood pressure, and perceptual changes during the treatment session. These effects are generally short-lived and closely monitored by medical staff to ensure safety and comfort, and cease shortly following the appointment.
Ketamine is not recommended for individuals with a history of psychosis, uncontrolled hypertension, certain cardiac conditions, or active substance abuse without prior stabilization. A thorough medical and psychiatric evaluation is necessary to determine safety.
The number of ketamine treatments needed for depression varies by individual. Most patients begin with a series of 6 to 8 sessions over several weeks. Some people notice improvement after the first few treatments, while others require additional sessions to experience sustained relief.
Discover the healing power of ketamine therapy in the serene Wasatch Mountains, an ideal setting to overcome a long battle with chronic depression. Connect with our team today and find out if you’re eligible for treatment.
Google Reviews
Jacob Fulton
What a great experience. Our household has been super sick and most of us haven’t been able to keep fluids down. This is exactly what we needed to get strength and energy back. Annie was so good at the poke that we barely felt it.
KariLyn Cox
What a great experience. Our household has been super sick and most of us haven’t been able to keep fluids down. This is exactly what we needed to get strength and energy back. Annie was so good at the poke that we barely felt it.
Justin Seegmiller
Saw Dr Johnson and she was very kind and the clinic was very helpful. She asked questions and listened to my issues. So far I would recommend this clinic. Harper C is fairly new. Hope people hea4 more about this place.
Marc Pinnegar
Jean Ann is great to work with. She has helped me tremendously with my gi and low T issues. I recommend her to everyone I know.
B Huntsman
Harper Clinic is incredible! The staff is absolutely beautiful, classy, and so personable—they make you feel right at home. The injection process was quick and easy, and I immediately felt healthier and more energized afterward. This clinic is a gem, and I can’t recommend it enough! Thank you, Harper Clinic, for keeping me feeling my best!
Olivia Hymas
Emily is my girlllll. They all slay so hard, and my mom and I both noticed a difference in my OCD. They also remap you if you don’t notice a difference after a few weeks, which is super nice.
Shalyn Bills
Love this place! The staff is incredible definitely give it a try. 10/10 recommend
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